Roche’s news also reminds us of a broader challenge. Many of today’s genetic therapies are scientifically remarkable, but ...

8 min read | July was a hard month for Huntington’s disease research, with Roche ending two HD programs. But the month also ...

A recent publication presents the results of a clinical trialclinical trial Very carefully planned experiments designed to ...

This study moves MutLβ from being a semi-unknown quantity in somatic expansion to a defined member of the responsible team.

On 25th June 2024, Wave Life Sciences shared the results of their SELECT-HD clinical trialclinical trial Very carefully planned experiments designed to answer specific questions about how a drug ...

HDBuzz: 2024 was a big year for HD research, particularly in the clinical space. Which breakthroughs or advances in HD research from the past year are you particularly excited about? HDBuzz Editors-in ...

In plain language. Written by scientists. Heart health has been linked to lower levels of NfL, a key biomarker of brain cell damage in Huntington’s disease. This suggests heart-healthy habits – like ...

⏱️7 min read | A recent study in pigs suggests the HD brain could be under attack from the body’s own immune system. The results reveal that invading cytotoxic T cells might contribute to ...

Imagine the gene that causes Huntington’s disease (HD) as a vast river. At its source is the CAG repeatCAG repeat The stretch of DNA at the beginning of the HD gene, which contains the sequence CAG ...

An international collaboration between world leaders in Huntington’s disease (HD) that spans both academia and pharmaceutical companies is giving us new insight into how HD progresses. This study has ...

Seeking dental care and adhering to recommended routines is tough for lots of folks, even under the best of circumstances. Throw Huntington’s disease (HD) into the mix, and oral health can get even ...