A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

Eukaryotic chromosomes replicate from multiple discrete loci termed origins of replication. These sites are first recognised by the origin recognition complex (ORC), which, together with Cdc6 and Cdt1 ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

King Abdullah University of Science & Technology (KAUST)Mar 19 2025 Reviewed For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

An international research team has recovered ancient human mitochondrial and nuclear DNA directly from cave wall materials in ...